Also called: Ebola hemorrhagic fever, Ebola virus disease. Ebola hemorrhagic fever is caused by a virus. The early symptoms of Ebola are similar to other, more common, diseases. Ebola virus is one of five known viruses within the genus Ebolavirus. Four of the five known ebolaviruses, including EBOV, cause a severe and often fatal Family: Filoviridae. ¿Qué es el ébola? El ébola es una de las enfermedades que se conocen como fiebres hemorrágicas. La causa de estas enfermedades son virus que provocan.
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Ebola virus - Wikipedia
The outer viral envelope of the virion is derived by budding from domains of host cell membrane into which the GP spikes have been inserted during their biosynthesis. Viral proteins VP40 and VP24 que es ebola located between the envelope and the nucleocapsid see followingin the matrix space.
This viral genome codes for seven structural proteins and one non-structural protein. Sections of que es ebola NP, VP35 and the L genes from filoviruses have been identified as endogenous in the genomes of several groups of small mammals.
Like other RNA viruses  the Ebola virus mutates rapidly, both within a person during the progression of disease and in the reservoir among the local human population.
The first is a cholesterol transporter protein, the host-encoded Niemann—Pick C1 NPC1which appears to que es ebola essential for entry of Ebola virions into the host cell and for its ultimate replication.
The same studies described similar results regarding NPC1's role in virus entry for Marburg virusa related filovirus. Silencing its effect with siRNA prevented infection of Vero cells.
Together, these studies suggest NPC1 and TIM-1 may be potential therapeutic targets for an Ebola anti-viral que es ebola and as a basis for a rapid field diagnostic assay.
These then self-assemble into viral macromolecular structures in the host cell.
The virus begins its attack by attaching to host receptors through the glycoprotein GP surface peplomer and is endocytosed que es ebola macropinosomes in the host cell. Encapsidated, negative-sense genomic ssRNA is used as a template for the synthesis 3'-5' of polyadenylated, monocistronic mRNAs and, using the host cell's ribosomes, tRNA molecules, etc.
These two molecules assemble, first into heterodimers, and then into trimers to give the surface peplomers. Secreted glycoprotein sGP precursor is cleaved to que es ebola and delta peptide, both of which are released from the cell.
Virus del Ébola y virus de Marburgo - Síntomas y causas - Mayo Clinic
As viral protein levels rise, a switch occurs from translation to replication. The newly formed nucleocapsids and envelope proteins associate at the host cell's plasma membrane; budding occurs, destroying the cell.
Intermediary hosts have been que es ebola to be "various species of fruit bats Evidence of infection in bats has been detected through molecular and serologic means.
However, ebolaviruses que es ebola not been isolated in bats.
Pigs in the Philippines have been reported to be infected with Reston virusso other interim or amplifying hosts may exist. Ebola virus disease Ebola virus is one of the four ebolaviruses known to cause disease in humans.
The que es ebola causes the shutdown of other vital organs such as liver and lungs too.
In fact, it is able to invade almost all human cells que es ebola different attachment mechanisms for each cell type except for lymphocytes. The very cells that are meant to fight infection are used as carriers to spread infection to other body parts 5. It has been found that the ebola-infected cells do not undergo normal apoptosis, but exhibit vacuolization and signs of necrosis.
Symptoms[ change change source ] When que es ebola get Ebola the first symptoms look like some other diseases. People get a fever and feel very tired.
Their headstomachjointsand throat might hurt. Sometimes, people think they have other diseases like malaria or typhoid que es ebola.
Later, people get much sicker. They bleed both inside and outside their bodies.